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Application of Atropine Injection in the Treatment of Ruminant Diseases

Received: 10 February 2023     Accepted: 27 February 2023     Published: 21 March 2023
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Abstract

Atropine is one of the commonly used drugs for clinical treatment of livestock and poultry, as well as one of the commonly used drugs for animal emergency treatment. Its main components are d-hyoscyamine and L-hyoscyamine. Atropine is a toxic colorless, odorless or white crystalline alkaloid extracted from belladonna and other solanaceous plants. It is neutral or weakly acidic when dissolved in water. Atropine is mainly an m-receptor blocker, belonging to anticholinergic drugs. It can compete with acetylcholine for M-choline receptor, thus blocking the M-like effect of acetylcholine. Atropine has a very high selectivity in blocking M receptor, and large doses can also block ganglion N1 receptor. It mainly acts on smooth muscle, relieves small vessel spasm, improves microcirculation, inhibits gland secretion, relieves vagus nerve inhibition on heart, accelerates heart beat, dilates pupils, increases intraocular pressure, excites respiratory center, and relieves respiratory inhibition. It is applied to cases of ruminant diseases such as diarrhea in calves and lambs, toxic diseases in organic phosphorus, abdominal pain caused by parasitic diseases, gastrointestinal volvulus, administration before anesthesia, improvement of microcirculation, eye diseases, etc. through oral, subcutaneous, intramuscular and intravenous injection. However, the amount of treatment has no significant effect on blood vessels and blood pressure. A large dose of treatment can cause skin blood vessels to expand. A large dose of treatment can relieve small vessel spasm when microcirculation is impaired, and expand peripheral blood vessels to improve microcirculation.

Published in Animal and Veterinary Sciences (Volume 11, Issue 1)
DOI 10.11648/j.avs.20231101.15
Page(s) 27-29
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2023. Published by Science Publishing Group

Keywords

Atropine, Ruminants, Cattle, Sheep, Microcirculation

References
[1] Li Zhe. Application of atropine in veterinary clinic [J]. Jilin Animal Husbandry and Veterinary Medicine, 2016, 37 (10): 47.
[2] Liu Yanhua. Several keys in the treatment of livestock organophosphorus pesticide poisoning [J]. Hunan Animal Husbandry and Veterinary Medicine, 2013 (01): 24-26.
[3] Wu Bingqiao, Zhang Shirong, Yang Pingchuan. Observation and clinical application of bovine fundus [J]. Journal of Henan Agricultural University, 1984 (01): 69-77.
[4] Zhai Xiaohu. Study on the effect and pharmacokinetics of intravenous combined anesthesia with diazepam and ketamine in dogs [D]. Nanjing Agricultural University, 2007.
[5] Sun Zhentao. Experimental Study on Anesthesia Management and Lung Protection of Brain Death Model [D]. Zhengzhou University, 2005.
[6] Clarke RS; Dundee JW; Mooer J; Studies of drugs given beforeanaesthesia. [J] British Journal of Anaesthesia, 1964.
[7] Liang Xueyong; Diagnosis and treatment of atropine overdose in domestic animals [J]. Veterinarian's Guide. 2007 (08).
[8] Ling kwok-sun; Clinical application of atropine [J]. Journal of Veterinary Science. 1984 (11).
[9] WooFai Chung; Qinghai; Clinical application of atropine [J]. Journal of Animal Husbandry and veterinary medicine. 2005 (06).
[10] Kang.; Qingzengan and atropine mixture in the treatment of porcine diarrhea [J]. Animal husbandry and veterinary medicine in Liaoning province. 1997 (05).
[11] Cheung kwok-shek; Atropine's principles for the use of first aid in animal Organophosphate poisoning [J]. Chinese Journal of Veterinary Medicine. 2001 (09).
[12] Palindrome; Atropine was used to treat swine diarrhea with miraculous effect [J]. Northern livestock. 2008 (05).
[13] Kang shine; Prevention and treatment of uterine prolapse in dairy cows with integrated traditional Chinese and Western medicine [J]. Animal husbandry and veterinary medicine in Gansu province. 2011 (06).
[14] Sun Liying; Types and characteristics of veterinary narcotic drugs [J]. Technical Advisor on farming. 2009 (06).
[15] Xu Peng; Gao Baihua; Wu Shiliang; Liu Peng; Zhang Jiyuan. Injecting animals with narcotic drugs [J]. Feed Expo. 2019 (01).
Cite This Article
  • APA Style

    Haosheng Huang, Qiong Yang, Cuili Liu, Canshan Huang, Lini Yang, et al. (2023). Application of Atropine Injection in the Treatment of Ruminant Diseases. Animal and Veterinary Sciences, 11(1), 27-29. https://doi.org/10.11648/j.avs.20231101.15

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    ACS Style

    Haosheng Huang; Qiong Yang; Cuili Liu; Canshan Huang; Lini Yang, et al. Application of Atropine Injection in the Treatment of Ruminant Diseases. Anim. Vet. Sci. 2023, 11(1), 27-29. doi: 10.11648/j.avs.20231101.15

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    AMA Style

    Haosheng Huang, Qiong Yang, Cuili Liu, Canshan Huang, Lini Yang, et al. Application of Atropine Injection in the Treatment of Ruminant Diseases. Anim Vet Sci. 2023;11(1):27-29. doi: 10.11648/j.avs.20231101.15

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  • @article{10.11648/j.avs.20231101.15,
      author = {Haosheng Huang and Qiong Yang and Cuili Liu and Canshan Huang and Lini Yang and Yuanxing Lei and Guochun Tang},
      title = {Application of Atropine Injection in the Treatment of Ruminant Diseases},
      journal = {Animal and Veterinary Sciences},
      volume = {11},
      number = {1},
      pages = {27-29},
      doi = {10.11648/j.avs.20231101.15},
      url = {https://doi.org/10.11648/j.avs.20231101.15},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.avs.20231101.15},
      abstract = {Atropine is one of the commonly used drugs for clinical treatment of livestock and poultry, as well as one of the commonly used drugs for animal emergency treatment. Its main components are d-hyoscyamine and L-hyoscyamine. Atropine is a toxic colorless, odorless or white crystalline alkaloid extracted from belladonna and other solanaceous plants. It is neutral or weakly acidic when dissolved in water. Atropine is mainly an m-receptor blocker, belonging to anticholinergic drugs. It can compete with acetylcholine for M-choline receptor, thus blocking the M-like effect of acetylcholine. Atropine has a very high selectivity in blocking M receptor, and large doses can also block ganglion N1 receptor. It mainly acts on smooth muscle, relieves small vessel spasm, improves microcirculation, inhibits gland secretion, relieves vagus nerve inhibition on heart, accelerates heart beat, dilates pupils, increases intraocular pressure, excites respiratory center, and relieves respiratory inhibition. It is applied to cases of ruminant diseases such as diarrhea in calves and lambs, toxic diseases in organic phosphorus, abdominal pain caused by parasitic diseases, gastrointestinal volvulus, administration before anesthesia, improvement of microcirculation, eye diseases, etc. through oral, subcutaneous, intramuscular and intravenous injection. However, the amount of treatment has no significant effect on blood vessels and blood pressure. A large dose of treatment can cause skin blood vessels to expand. A large dose of treatment can relieve small vessel spasm when microcirculation is impaired, and expand peripheral blood vessels to improve microcirculation.},
     year = {2023}
    }
    

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  • TY  - JOUR
    T1  - Application of Atropine Injection in the Treatment of Ruminant Diseases
    AU  - Haosheng Huang
    AU  - Qiong Yang
    AU  - Cuili Liu
    AU  - Canshan Huang
    AU  - Lini Yang
    AU  - Yuanxing Lei
    AU  - Guochun Tang
    Y1  - 2023/03/21
    PY  - 2023
    N1  - https://doi.org/10.11648/j.avs.20231101.15
    DO  - 10.11648/j.avs.20231101.15
    T2  - Animal and Veterinary Sciences
    JF  - Animal and Veterinary Sciences
    JO  - Animal and Veterinary Sciences
    SP  - 27
    EP  - 29
    PB  - Science Publishing Group
    SN  - 2328-5850
    UR  - https://doi.org/10.11648/j.avs.20231101.15
    AB  - Atropine is one of the commonly used drugs for clinical treatment of livestock and poultry, as well as one of the commonly used drugs for animal emergency treatment. Its main components are d-hyoscyamine and L-hyoscyamine. Atropine is a toxic colorless, odorless or white crystalline alkaloid extracted from belladonna and other solanaceous plants. It is neutral or weakly acidic when dissolved in water. Atropine is mainly an m-receptor blocker, belonging to anticholinergic drugs. It can compete with acetylcholine for M-choline receptor, thus blocking the M-like effect of acetylcholine. Atropine has a very high selectivity in blocking M receptor, and large doses can also block ganglion N1 receptor. It mainly acts on smooth muscle, relieves small vessel spasm, improves microcirculation, inhibits gland secretion, relieves vagus nerve inhibition on heart, accelerates heart beat, dilates pupils, increases intraocular pressure, excites respiratory center, and relieves respiratory inhibition. It is applied to cases of ruminant diseases such as diarrhea in calves and lambs, toxic diseases in organic phosphorus, abdominal pain caused by parasitic diseases, gastrointestinal volvulus, administration before anesthesia, improvement of microcirculation, eye diseases, etc. through oral, subcutaneous, intramuscular and intravenous injection. However, the amount of treatment has no significant effect on blood vessels and blood pressure. A large dose of treatment can cause skin blood vessels to expand. A large dose of treatment can relieve small vessel spasm when microcirculation is impaired, and expand peripheral blood vessels to improve microcirculation.
    VL  - 11
    IS  - 1
    ER  - 

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Author Information
  • Animal Husbandry Management Station of Mengshan County, Wuzhou City, China

  • Animal Epidemic Disease Prevention and Control Center of Pingle County, Guilin City, China

  • Agricultural and Rural Comprehensive Service Center of Chentang Town, Mengshan County, Wuzhou City, China

  • Animal Husbandry Management Station of Mengshan County, Wuzhou City, China

  • Animal Husbandry Management Station, Guigang City, China

  • Animal Disease Prevention and Control Center of Mengshan County, Wuzhou City, China

  • Animal Disease Prevention and Control Center of Mengshan County, Wuzhou City, China

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