| Peer-Reviewed

The Epidemiological Survey and Analysis of Canine Babesiosis in Xi’an City, China

Received: 8 July 2018     Accepted: 23 July 2018     Published: 21 August 2018
Views:       Downloads:
Abstract

The canine babesiosis is one of the major diseases that significantly harm to the dogs. In order to analyze the characteristics of babesiosis in dogs, and to explore the characteristics of blood changes in canine babesiosis in Xi’an city, 194 cases of canine babesiosis were diagnosed in the animal teaching hospital of the Northwest A&F University during January 2013 to December 2015. The results showed that autumn was the main season for canine babesiosis in Xi’an city, male dogs under 3 years old were the main pathogenic group, and Teddy dog is the most susceptible breed. In addition, the number of red blood cell, platelet, hematokrit, hemoglobin, eosinophil granulocyte and the concentration of calcium were decreased; the mean corpuscular volume, the number of white blood cell, the concentration of alkaline phosphatase, total bilirubin, urea nitrogen, phosphorus, alanine aminotransferase and aspartate aminotransferase was elevated. Moreover, the liver and kidney function was also destroyed in a certain degree. It indicated that the dogs suffered from severe anemia (regenerative anemia), accompanied by inflammatory reaction, which can cause the blood coagulation dysfunction, some drugs with protecting liver and kidney should be used in the process of treatment so as to improve the cure rate of this disease. These findings provided important reference information for the prevention and treatment of babesiosis.

Published in Animal and Veterinary Sciences (Volume 6, Issue 3)
DOI 10.11648/j.avs.20180603.12
Page(s) 43-50
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

Canine Babesiosis, Blood Routine Test, Biochemical Criterion, Case Analysis

References
[1] Abdullahi S U, Mohammed A A, Trimnell A R, et al., 1990. Clinical and haematological findings in 70 naturally occurring cases of canine babesiosis. Journal of Small Animal Practice. 31, 145–147.
[2] Kuleš J, Torre-Minguela C, Barić R R, et al., 2016. Plasma biomarkers of SIRS and MODS associated with canine babesiosis. Research in Veterinary Science. 105, 222–228.
[3] Josipa K, Jelena G, Vladimir M, et al., 2017. Alteration of haemostatic parameters in uncomplicated canine babesiosis. Comparative Immunology Microbiology and Infectious Disease. 53, 1–6.
[4] Gad Baneth, 2018. Antiprotozoal treatment of canine babesiosis. Veterinary Parasitology. 254, 58–63.
[5] Shekerah P, Lavoisier A, Samantha S, et al., 2018. Screening of patient blood samples for babesiosis using enzymatic assays. Ticks and Tick-borne Disease. 9, 302–306.
[6] Birkenheuer A J, Levy M G, Stebbins M, 2003. Atovaquone and azithromycin combination therapy for the treatment of Babesia gibsoni infections in dogs. Journal Veterinary Internal Medicine. 17, 381–382.
[7] Kong F Y, 1997. Animal parasitology [M]. Beijing: China agricultural university press. 315–316.
[8] Hou J F, 2002. Small animal diseases. [M]. Beijing: China agricultural university press. 182–184.
[9] Greene C E, 2012. Infectious diseases of the dog and cat. Saunders; Elsevier Inc. 773–775.
[10] Welzl C, Leisewitz A L, Jacobson L S, et al., 2001. Systemic inflammatory response syndrome and multiple-organ damage/dysfunction in complicated canine babesiosis. Journal of the South African Veterinary Association-tydsrif Vandie Suid-a 72, 158–162.
[11] Matijatko V, Torti M, Schetters T P, 2012. Canine babesiosis in Europe: how many diseases? Trends in Parasitology. 28, 99–105.
[12] Wojciech Z, Olga G Z, Piotr B, et al., 2015. Low T3 syndrome in canine babesiosis associated with increased serum IL-6 concentration and azotaemia. Veterinary Parasitology. 211, 23–27.
[13] Michael L, Georges K, Alexander T, et al., 2008. Seasonal occurrence of canine babesiosis is influenced by local climate conditions. International Journal of Medicine and Microbiology. 298, 243–248.
[14] Birkenheuer A J, Levy M G, Stebbins M, et al., 2003. Serosurvey of anti Babesia antibodies in stray dogs and American pit bull terriers and American Staffordshire terriers from North Carolina. Journal of the American Animal Hospital Association. 39, 551–557.
[15] Vesna M, Ivana K, Marin T, et al., 2009. Septic shock in canine babesiosis. Veterinary Parasitology. 162, 263–270.
[16] Defauw P, Schoeman J P, Smets P, et al., 2012. Assessment of renal dysfunction using urinary markers in canine babesiosis caused by Babesia rossi. Veterinary Parasitology. 190, 326–332.
[17] Birkenheuer A J, Neel J, Ruslander D, et al., 2004. Detection and molecular characterization of a novel large Babesia species in a dog. Veterinary Parasitology. 124, 151–160.
[18] Amelia G, Bo W, Johan P, 2013. Schoeman, Annemarie T. Kristensen, Mads Kjelgaard-Hansen. Mortality in virulent canine babesiosis is associated with a consumptive coagulopathy. Veterinary Journal. 196, 213–217.
[19] Bohm M, 2006. The comparative assessment of Babesia rossi capillary and venous blood parasitaemias on thin blood smears and their association with disease manifestations. Thesis, University of Pretoria, South Africa.
[20] Boozer A L and Macintire D K, 2003. Canine babesiosis. Veterinary Clinics of North American Small Animal Practice. 33, 885–904.
[21] Bosman A M, Venter E H, Penzhorn B L, 2006. Occurrence of Babesia felis and Babesia leo in various wild felid species and domestic cats in Southern Africa, based on reverse line blot analsis. Veterinary Parasitology. 144, 33–38.
[22] Bourdoiseau G, 2006. Canine babesiosis in France. Veterinary Parasitology, 138, 118–125.
Cite This Article
  • APA Style

    Wuren Ma, Yunpeng Fan, Feng Jie, Lingyu Zhang, Yuan Zhong, et al. (2018). The Epidemiological Survey and Analysis of Canine Babesiosis in Xi’an City, China. Animal and Veterinary Sciences, 6(3), 43-50. https://doi.org/10.11648/j.avs.20180603.12

    Copy | Download

    ACS Style

    Wuren Ma; Yunpeng Fan; Feng Jie; Lingyu Zhang; Yuan Zhong, et al. The Epidemiological Survey and Analysis of Canine Babesiosis in Xi’an City, China. Anim. Vet. Sci. 2018, 6(3), 43-50. doi: 10.11648/j.avs.20180603.12

    Copy | Download

    AMA Style

    Wuren Ma, Yunpeng Fan, Feng Jie, Lingyu Zhang, Yuan Zhong, et al. The Epidemiological Survey and Analysis of Canine Babesiosis in Xi’an City, China. Anim Vet Sci. 2018;6(3):43-50. doi: 10.11648/j.avs.20180603.12

    Copy | Download

  • @article{10.11648/j.avs.20180603.12,
      author = {Wuren Ma and Yunpeng Fan and Feng Jie and Lingyu Zhang and Yuan Zhong and Weimin Zhang and Xiaoping Song},
      title = {The Epidemiological Survey and Analysis of Canine Babesiosis in Xi’an City, China},
      journal = {Animal and Veterinary Sciences},
      volume = {6},
      number = {3},
      pages = {43-50},
      doi = {10.11648/j.avs.20180603.12},
      url = {https://doi.org/10.11648/j.avs.20180603.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.avs.20180603.12},
      abstract = {The canine babesiosis is one of the major diseases that significantly harm to the dogs. In order to analyze the characteristics of babesiosis in dogs, and to explore the characteristics of blood changes in canine babesiosis in Xi’an city, 194 cases of canine babesiosis were diagnosed in the animal teaching hospital of the Northwest A&F University during January 2013 to December 2015. The results showed that autumn was the main season for canine babesiosis in Xi’an city, male dogs under 3 years old were the main pathogenic group, and Teddy dog is the most susceptible breed. In addition, the number of red blood cell, platelet, hematokrit, hemoglobin, eosinophil granulocyte and the concentration of calcium were decreased; the mean corpuscular volume, the number of white blood cell, the concentration of alkaline phosphatase, total bilirubin, urea nitrogen, phosphorus, alanine aminotransferase and aspartate aminotransferase was elevated. Moreover, the liver and kidney function was also destroyed in a certain degree. It indicated that the dogs suffered from severe anemia (regenerative anemia), accompanied by inflammatory reaction, which can cause the blood coagulation dysfunction, some drugs with protecting liver and kidney should be used in the process of treatment so as to improve the cure rate of this disease. These findings provided important reference information for the prevention and treatment of babesiosis.},
     year = {2018}
    }
    

    Copy | Download

  • TY  - JOUR
    T1  - The Epidemiological Survey and Analysis of Canine Babesiosis in Xi’an City, China
    AU  - Wuren Ma
    AU  - Yunpeng Fan
    AU  - Feng Jie
    AU  - Lingyu Zhang
    AU  - Yuan Zhong
    AU  - Weimin Zhang
    AU  - Xiaoping Song
    Y1  - 2018/08/21
    PY  - 2018
    N1  - https://doi.org/10.11648/j.avs.20180603.12
    DO  - 10.11648/j.avs.20180603.12
    T2  - Animal and Veterinary Sciences
    JF  - Animal and Veterinary Sciences
    JO  - Animal and Veterinary Sciences
    SP  - 43
    EP  - 50
    PB  - Science Publishing Group
    SN  - 2328-5850
    UR  - https://doi.org/10.11648/j.avs.20180603.12
    AB  - The canine babesiosis is one of the major diseases that significantly harm to the dogs. In order to analyze the characteristics of babesiosis in dogs, and to explore the characteristics of blood changes in canine babesiosis in Xi’an city, 194 cases of canine babesiosis were diagnosed in the animal teaching hospital of the Northwest A&F University during January 2013 to December 2015. The results showed that autumn was the main season for canine babesiosis in Xi’an city, male dogs under 3 years old were the main pathogenic group, and Teddy dog is the most susceptible breed. In addition, the number of red blood cell, platelet, hematokrit, hemoglobin, eosinophil granulocyte and the concentration of calcium were decreased; the mean corpuscular volume, the number of white blood cell, the concentration of alkaline phosphatase, total bilirubin, urea nitrogen, phosphorus, alanine aminotransferase and aspartate aminotransferase was elevated. Moreover, the liver and kidney function was also destroyed in a certain degree. It indicated that the dogs suffered from severe anemia (regenerative anemia), accompanied by inflammatory reaction, which can cause the blood coagulation dysfunction, some drugs with protecting liver and kidney should be used in the process of treatment so as to improve the cure rate of this disease. These findings provided important reference information for the prevention and treatment of babesiosis.
    VL  - 6
    IS  - 3
    ER  - 

    Copy | Download

Author Information
  • College of Veterinary Medicine, Northwest A&F University, Yangling, P. R. China

  • College of Veterinary Medicine, Northwest A&F University, Yangling, P. R. China

  • College of Veterinary Medicine, Northwest A&F University, Yangling, P. R. China

  • College of Veterinary Medicine, Northwest A&F University, Yangling, P. R. China

  • College of Veterinary Medicine, Northwest A&F University, Yangling, P. R. China

  • College of Veterinary Medicine, Northwest A&F University, Yangling, P. R. China

  • College of Veterinary Medicine, Northwest A&F University, Yangling, P. R. China

  • Sections